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Health

What Happens in Brain During Sleep Deprivation? New Study Reveals Details

Last updated: January 21, 2026 11:31 pm
Irma Khan
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Scientists have identified a remarkable and unusual process that occurs in the brains of people suffering from sleep deprivation.

According to new research, difficulties in maintaining focus, slower reaction times, and reduced cognitive ability after poor sleep are not just the result of fatigue but are linked to a specific biological process taking place in the brain.

Researchers at the Massachusetts Institute of Technology (MIT) studied the changes that occur in the brain when sleep is insufficient. They found that under such conditions, the movement of a particular fluid in the brain increases, temporarily affecting the ability to concentrate.

The study explains that cerebrospinal fluid (CSF), which normally moves during sleep to clear waste products accumulated in the brain throughout the day, is essential for brain health. However, in the case of sleep deprivation, this system becomes active even during wakefulness.

Scientists say that when CSF moves while a person is awake, the brain struggles to maintain focus. This process is the brain’s attempt to compensate for the lack of sleep, but it comes at the immediate cost of reduced attention.

The study involved 26 volunteers who underwent tests in two phases: one after sleep deprivation and the other following a full night’s sleep. Brain functions were assessed the next morning through various cognitive tasks. The findings were published in the scientific journal Nature Neuroscience.

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